Microvesicles - Tissue Factor (MV-TF) activity measurement

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To improve standardization of studies measuring Tissue Factor of Microvesicles (TF activity), the International Society on Thrombosis and Haemostasis (ISTH) has published international guidelines in 2019 based ona a careful review of current and historical peer-reviewed publications[Nieuwland et al.]

Minimally, the ISTH guideline recommends: 

  • Kinetic determination of Microvesicles - Tissue Factor (MV-TF) dependant factor Xa generation 
  • Anti-TF antibody to inhibit TF coagulant activity and to ensure optimal assay specificity 
  • TF calibrator to standardize procoagulant activity measurement  


CY-QUANT MV-TF, the newest TF Assay is a chromogenic assay. Featuring a highly sensitive solution for MV TF activity, without losing specificity, all while fitting with international guidelines

Test principle of CY-QUANT MV-TF Activity by Stago. Measurement of microvesicles tissue factor activity with a kinetic determination of MV-TF dependent factor Xa Generation.
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CY-QUANT MV-TF Activity brochure.
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CY-QUANT MV-TF Activity brochure cover

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