PLATELET Calibrator

    default
    Reference
    7011
    Status
    RUO
    Sample
    50 µl citrated or CTAD whole blood
    Quantity
    50 tests
    Detection
    Fluorescent
    fiche specification
    Fluorescent
    gamme mesure
    500 to 100,000 glycoproteins
    Application
    Flow Cytometry Kits
    Form

    - Diluent, 10 fold concentrated - Negative isotypic control IgG1 - Negative isotypic control IgG2a - Negative isotypic control IgG2b - Calibrated bead suspension - Staining reagent, polyclonal anti mouse IgG-FITC

    Additional information
    5 calibration curves

    Calibration kit for the measurement of platelet glycoprotein expression level or any other human platelet surface molecules. Platelets are stained by no wash indirect immunofluorescence with specific monoclonal antibodies (MAbs) of your choice and analyzed by quantitative flow cytometry. The expression level of the tested antigen is determined using the calibration beads.This protocol is designed for purified mouse MAbs of IgG1, IgG2a and IgG2b isotypes.

    Date Document Name Download
    01/09/2010 APPENDIX PLATELET Calibrator EN (104.58 KB)
    FR (115.01 KB)
    01/09/2010 Package insert PLATELET Calibrator EN (150.67 KB)
    FR (140.40 KB)
    01/02/2018 Package insert PLATELET Calibrator EN (122.90 KB)
    FR (123.05 KB)
    Author Title Year of edition Review
    Dupont A et al.
    An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN
    2003
    Blood
    Best D et al.
    GpVI levels in platelets: relationship to platelet function at high shear
    2003
    Blood
    Hughan SC et al.
    Selective impairment of platelet activation to collagen in the absence of GATA1
    2005
    Blood
    Fontana P et al.
    Identification of functional polymorphisms of the thromboxane A2 receptor gene in healthy volunteers
    2006
    Thromb Haemost
    Senis et al.
    The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis
    2009
    Blood
    Protty MB et al.
    Identification of Tspan9 as a novel platelet tetraspanin and the collagen receptor GPVI as a component of tetraspanin microdomains
    2009
    Biochem. J.
    Mangin P.H. et al.
    A humanized GPVI mouse model to assess the antithrombotic efficacy of anti-GPVI agents
    2012
    J Pharmacol Exp Ther.